Stagioni Regolari 4

1. 

   Jonny Lee Miller

   Sherlock Holmes

2. 

   Lucy Liu

   Joan Watson

3. 

   Jon Michael Hill

   Marcus Bell

4. 

   Aidan Quinn

   Thomas Gregson

Guest Stars 12

1. 

   John Noble

   Morland Holmes

2. 

   Kristen Bush

   Annie Spellman

3. 

   Charlie Semine

   Stewart Pringle/Wilson Kubiak

4. 

   Jodi Long

   Mrs. Tseng

5. 

   January LaVoy

   Chloe

6. 

   Eric Elizaga

   Eldon

7. 

   Kristoffer Cusick

   Gene

8. Gabe Doran

   Propane Salesman

9. 

   Roderick Hill

   Wesley Conrad

10. 

    Lizbeth MacKay

    Mrs. Conrad

11. 

    James Frain

    Odin Reichenbach

12. 

    Rachael Holmes

    Antonia

Troupe 2