Stała obsada sezonu 16

1. 

   Ellen Pompeo

   Meredith Grey

2. 

   Chandra Wilson

   Miranda Bailey

3. 

   James Pickens Jr.

   Richard Webber

4. 

   Kevin McKidd

   Owen Hunt

5. 

   Caterina Scorsone

   Amelia Shepherd

6. 

   Camilla Luddington

   Jo Wilson

7. 

   Kim Raver

   Teddy Altman

8. 

   Chris Carmack

   Atticus Lincoln

9. 

   Anthony Hill

   Winston Ndugu

10. 

    Kelly McCreary

    Maggie Pierce

11. 

    Adelaide Kane

    Jules Millin

12. 

    Alexis Floyd

    Simone Griffith

13. 

    Niko Terho

    Lucas Adams

14. 

    Harry Shum Jr.

    Benson 'Blue' Kwan

15. 

    Jake Borelli

    Levi Schmitt

16. 

    Midori Francis

    Mika Yasuda

Goście specjalni 21

1. 

   Jason George

   Ben Warren

2. 

   Scott Speedman

   Nick Marsh

3. 

   Jaicy Elliot

   Taryn Helm

4. Branden Silverman

   Paramedic

5. Rasta Thomas

   Paramedic

6. Janai Kaylani

   Pru Miller

7. Aniela Gumbs

   Zola Grey Shepherd

8. 

   Ella Faris

   Ellis Shepherd

9. 

   Gracie Faris

   Ellis Shepherd

10. Brody Goodstadt

    Derek Bailey Shepherd

11. Ryder Goodstadt

    Derek Bailey Shepherd

12. Ryker Murphy

    Scout

13. Ryden Murphy

    Scout

14. 

    T.J. Ramini

    Mr. Al-Hasan

15. 

    Brian Letscher

    Mr. Epley

16. Gio Schwab

    River Epley

17. Betsy Stover

    Nurse Stacy

18. Emily Anderson

    Luna

19. Naomi Anderson

    Luna

20. 

    Michelle Cortés

    Isla

21. Ryan Pekar

    Jarah Al-Hasan

Ekipa 2