Elenco principal da temporada 21

1. 

   Dominic West

   Jimmy McNulty

2. 

   Lance Reddick

   Cedric Daniels

3. 

   Sonja Sohn

   Kima Greggs

4. 

   Wendell Pierce

   Bunk Moreland

5. 

   Michael Kenneth Williams

   Omar Little

6. 

   Deirdre Lovejoy

   Rhonda Pearlman

7. 

   Clarke Peters

   Lester Freamon

8. 

   J.D. Williams

   Bodie Broadus

9. 

   Jamie Hector

   Marlo Stanfield

10. 

    Andre Royo

    Bubbles

11. 

    Frankie Faison

    Ervin Burrell

12. 

    Aidan Gillen

    Tommy Carcetti

13. 

    John Doman

    William Rawls

14. 

    Seth Gilliam

    Ellis Carver

15. 

    Domenick Lombardozzi

    Herc

16. 

    Corey Parker Robinson

    Leander Sydnor

17. 

    Reg E. Cathey

    Norman Wilson

18. 

    Jim True-Frost

    Roland Pryzbylewski

19. 

    Robert Wisdom

    Howard "Bunny" Colvin

20. 

    Chad L. Coleman

    Dennis "Cutty" Wise

21. 

    Glynn Turman

    Clarence Royce

Convidados Especiais 10

1. 

   Delaney Williams

   Sgt. Jay Landsman

2. 

   Rick Otto

   Off. Kenneth Dozerman

3. 

   Gbenga Akinnagbe

   Chris Partlow (uncredited)

4. 

   Felicia Pearson

   Felicia 'Snoop' Pearson

5. 

   Maestro Harrell

   Randy Wagstaff

6. 

   Melanie Nicholls-King

   Cheryl

7. 

   Chad L. Coleman

   Dennis 'Cutty' Wise

8. 

   Cyrus Farmer

9. 

   Ramón Rodríguez

   Renaldo

10. 

    Marlyne Barrett

    Council President Nerese Campbell

Equipa técnica 2