Elenco principal da temporada 4

1. 

   Jared Padalecki

   Sam Winchester

2. 

   Jensen Ackles

   Dean Winchester

3. 

   Misha Collins

   Castiel

4. 

   Mark Sheppard

   Crowley

Convidados Especiais 10

1. 

   Timothy Omundson

   Cain

2. 

   Julien Hicks

   Austin Reynolds

3. 

   Roman Blomme

   Tommy Tolliver

4. 

   Simon Chin

   Prison Guard

5. John Mackie

   Demon

6. 

   Keith Martin Gordey

   Warden Skieff

7. 

   Jesse James Pierce

   Crossroads Demon

8. 

   Andrew Neil McKenzie

   Young Demon

9. 

   Martin Budny

   Guard #2

10. 

    Ruth Connell

    Rowena MacLeod

Equipa técnica 2