Elenco principal da temporada 4

1. 

   Jared Padalecki

   Sam Winchester

2. 

   Jensen Ackles

   Dean Winchester

3. 

   Misha Collins

   Castiel

4. 

   Mark Sheppard

   Crowley

Convidados Especiais 13

1. 

   Katie Sarife

   Marie

2. 

   Joy Regullano

   Maeve

3. 

   Alyssa Lynch

   Siobhan

4. 

   Natalie Sharp

   Maggie

5. 

   Hannah Levien

   Calliope

6. 

   Kelli Ogmundson

   Alice

7. 

   Vivien Elizabeth Armour

   Katie

8. 

   Nina Winkler

   Kristen

9. 

   Alberta Mayne

   Mrs. Chandler

10. 

    Jannen Karr

    Principal Salazar

11. 

    Rachel Warkentin

    Tammy

12. 

    Georgia Beaty

    Yellow-Eyed Demon

13. 

    Jake Abel

    Adam Milligan / Michael

Equipa técnica 2