Регулярный состав сезона 6

1. 

   Frankie Muniz

   Malcolm

2. 

   Jane Kaczmarek

   Lois

3. 

   Bryan Cranston

   Hal

4. 

   Justin Berfield

   Reese

5. 

   Erik Per Sullivan

   Dewey

6. 

   Christopher Masterson

   Francis

Приглашённые звёзды 15

1. 

   Harry Groener

   Rudy

2. Rappin' Granny

   Althea

3. 

   Edward James Gage

   Steve

4. 

   Norma Michaels

   Ethel

5. Jackie Benoit

   Mrs. Jenkins

6. Victoria Stevens

   Mrs. Tompkins

7. 

   Eric Nenninger

   Eric Hansen

8. 

   Brenda Wehle

   Lavernia

9. 

   Sandy Ward

   Pete

10. 

    John Ennis

    Artie

11. 

    Dan Martin

    Malik

12. 

    Craig Lamar Traylor

    Stevie Kenarban

13. 

    Alex Morris

    Trey

14. 

    Edward James Gage

    Brian

15. 

    Gary Anthony Williams

    Abraham 'Abe' Kenarban

Съёмочный состав 4