毕业季，医学博士王扬鸣作为实习医生进入安康医院急诊科，被急诊主任关老大强塞给想辞职的路易做徒弟，遭到嫌弃。与王扬鸣同期入职的刘非能力超群，路易的藐视、刘非的碾压激发了王扬鸣的胜负欲。他不放过任何锻炼机会，不但成功摆脱了大家对研究型医学生的偏见，还收获了友情爱情，与路易、祖闻达和刘非组成“急诊四杰”。

該劇根據王成鋼的同名小説改編，講述醫學博士畢業生王揚鳴順利進入安康醫院實習,並與路清奇、祖聞達、劉非組成了“急診四傑”,四個性格迥異的醫生,在一次次急診工作中,關於人生、理想和生命的相互碰撞與思考,始終樂觀對待,笑看人生,堅守醫生作為最高理想的故事

該劇根據王成鋼的同名小説改編，講述醫學博士畢業生王揚鳴順利進入安康醫院實習,並與路清奇、祖聞達、劉非組成了“急診四傑”,四個性格迥異的醫生,在一次次急診工作中,關於人生、理想和生命的相互碰撞與思考,始終樂觀對待,笑看人生,堅守醫生作為最高理想的故事。

On the eve of graduation, Wang Yang Ming, who took reversing heart failure as his mission, had a disagreement with his supervisor in medical experiments, and resolutely decided to switch from scientific research to clinical practice, and successfully joined the emergency department of Ruiren Hospital, which ranked first in the country.

Wang Yang Ming's competitive instinct was aroused by his busy life in the emergency department, when he took risks to deal with ventricular fibrillation in the elderly, rescued heat stroke migrant workers, treated stroke patients, and so on, constantly refined his medical skills. At the same time , on the ward formed group named "four masters of emergency medicine" , which Yang's Ming is a part, alongside with Lu Qing Qi, Zu Wen Da and Liu Fei. Now four of them, witness each other's growth and change, gain friendship and love, and experience dispersion and separation on their ward.