Series Cast 50

1. 

   Chad Michael Murray

   Lucas Scott (24 Episodes)

2. 

   James Lafferty

   Nathan Scott (24 Episodes)

3. 

   Bethany Joy Lenz

   Haley James Scott (24 Episodes)

4. 

   Sophia Bush

   Brooke Davis (24 Episodes)

5. 

   Hilarie Burton

   Peyton Sawyer (24 Episodes)

6. 

   Jackson Brundage

   Jamie Scott (24 Episodes)

7. 

   Lee Norris

   Marvin 'Mouth' McFadden (24 Episodes)

8. 

   Lisa Goldstein Kirsch

   Millicent Huxtable (24 Episodes)

9. 

   Paul Johansson

   Dan Scott (24 Episodes)

10. 

    Antwon Tanner

    Antwon 'Skills' Taylor (24 Episodes)

11. 

    Ashley Rickards

    Sam Walker (19 Episodes)

12. Kate Voegele

    Mia Catalano (12 Episodes)

13. 

    Burgess Jenkins

    Bobby (8 Episodes)

14. 

    Daphne Zuniga

    Victoria Davis (7 Episodes)

15. 

    Joe Manganiello

    Owen Morello (7 Episodes)

16. Vaughn Wilson

    Fergie (7 Episodes)

17. Jaden Harmon

    Andre (7 Episodes)

18. Michael May

    Chuck (7 Episodes)

19. 

    Kelsey Asbille

    Gigi (6 Episodes)

20. 

    Cullen Moss

    Junk (6 Episodes)

21. 

    Evan Peters

    Jack Daniels (6 Episodes)

22. 

    Torrey DeVitto

    Carrie (5 Episodes)

23. 

    Robbie Jones

    Quentin Fields (5 Episodes)

24. 

    Keedar Whittle

    Nino Jones (4 Episodes)

25. 

    James Van Der Beek

    Adam Reese (4 Episodes)

26. 

    B.J. Britt

    Devon Fox (4 Episodes)

27. 

    Susan Walters

    Principal Rimkus (3 Episodes)

28. Bradley Evans

    Jerry (3 Episodes)

29. 

    Dawnn Lewis

    Denise Fields (3 Episodes)

30. 

    John Doe

    Mick Wolf (3 Episodes)

31. 

    Devin McGee

    Xavier (2 Episodes), Man (1 Episode)

32. 

    Michael Beasley

    Mike (1 Episode), Coach (2 Episodes)

33. 

    Gregory Harrison

    Paul Norris (3 Episodes)

34. 

    Cassandra Jean Amell

    Missy (2 Episodes)

35. 

    Ernest Waddell

    Derek Sommers (2 Episodes)

36. 

    Nick Lachey

    Nick Lachey (2 Episodes)

37. 

    Michaela McManus

    Lindsey Strauss (2 Episodes)

38. 

    Haviland Morris

    Olivia Pruitt (2 Episodes)

39. 

    Amy Tipton

    Waitress (1 Episode)

40. Terry Loughlin

    Dr. Milford (1 Episode)

41. 

    Bill Cobbs

    Gus (1 Episode)

42. Leland L. Jones

    Preacher (1 Episode)

43. 

    Tom Hillmann

    Lon (1 Episode)

44. 

    Robert Hy Gorman

    Mover (1 Episode)

45. Grace Potter

    Grace (1 Episode)

46. 

    Juliet Cesario

    Waitress (1 Episode)

47. 

    Spencer Wilding

    Chris (1 Episode)

48. 

    Kelley Davis

    Mrs. Skolnick (1 Episode)

49. 

    Alex Sgambati

    Peyton Actress #1 (1 Episode)

50. 

    Matthew Atkinson

    Nathan Actor (1 Episode)

Series Crew 56