Elenco principal da temporada 6

1. 

   Tom Selleck

   Frank Reagan

2. 

   Donnie Wahlberg

   Danny Reagan

3. 

   Bridget Moynahan

   Erin Reagan-Boyle

4. 

   Will Estes

   Jamie Reagan

5. 

   Len Cariou

   Henry Reagan

6. 

   Abigail Hawk

   Abigail Baker

Convidados Especiais 18

1. 

   Amy Carlson

   Linda Reagan

2. 

   Andrea Roth

   Kelly Davidson

3. 

   Nicholas Turturro

   Sgt. Anthony Renzulli

4. 

   Andrew Terraciano

   Sean Reagan

5. 

   Robert Clohessy

   Sid Gormley

6. 

   Tony Terraciano

   Jack Reagan

7. Dylan Moore

   Sydney Davenport

8. 

   Bruce Altman

   Mayor Frank Russo

9. 

   Ronald Guttman

   Claudio Calso

10. 

    James Colby

    Walter Ryder

11. 

    Florencia Lozano

    Sophia Calso

12. 

    James Preston

    Blake Woods

13. 

    Alexandra Metz

    Courtney Thurman

14. 

    Melissa Benoist

    Renee

15. Lars Stevens

    Pietro

16. 

    Philip Hoffman

    Lawyer

17. Brigitte Viellieu-Davis

    Rosario

18. 

    Alexis Suarez

    Cop #3

Equipa técnica 2