Elenco principal da temporada 6

1. 

   Alex O'Loughlin

   Steve McGarrett

2. 

   Scott Caan

   Danny 'Danno' Williams

3. 

   Grace Park

   Kono Kalakaua

4. 

   Daniel Dae Kim

   Chin Ho Kelly

5. 

   Masi Oka

   Dr. Max Bergman

6. 

   Michelle Borth

   Catherine Rollins

Convidados Especiais 10

1. 

   Ian Anthony Dale

   Adam Noshimuri

2. 

   Dennis Chun

   Duke Lukela

3. 

   Taylor Wily

   Kamekona Tupuola

4. 

   William Baldwin

   Frank Delano

5. 

   Mark Dacascos

   Wo Fat

6. 

   Christine Lahti

   Doris McGarrett

7. 

   Reiko Aylesworth

   Malia Waincroft

8. Donnell Jewell Williams

   Police Officer

9. Karl Herlinger

   Toothpick / Devon Akina

10. Ryan Moniz

    Paramedic #1

Equipa técnica 2