The Super Milk Chan Show, known in Japan as OH! Super Milk Chan, is an anime comedy about a foul-mouthed girl named Milk P. Chan, who is entrusted by the President of Everything to defend the world, even though she can do very little besides making popular culture references. Its American slogan, as a result, became "Wholesome? Probably not. Good for you? Definitely."

Super Milk Chan is produced in Japan by Studio Pierrot. The North American DVD release by A.D. Vision features two different English-dubbed versions: a straight translation of the Japanese version and an Americanized version with western pop culture references and short live-action skits featuring ADV voice cast members.