Nonnatus之家迎来了一位新成员，Valerie Dyer护士。一个脆弱的年轻人抓住了Fred和Violet的心，而Mary Cynthia修女的下落则是一个问题。

一个意外的转变导致婚礼被匆忙安排。Shelagh终于开始分娩。药丸的到来导致了不可预知的后果。

冬天还在继续，Nonnatus之家的团队欢迎他们最新的助产士，Lucille Anderson。Crane护士和Turner医生照顾一位面临被驱逐的老年癌症患者。

Lucille必须赢得一位对分娩感到恐惧的母亲的信任。Crane护士和Turner医生急于找到一个可能的天花患者。

团队必须团结起来，为Monica Joan修女的生日做准备。同时，附近的一家妇产医院的关闭给Nonnatus的助产士们带来了大量的准妈妈。

As Poplar prepares for Christmas, the nuns leave for the Mother House to vote in a new mother superior and to help care for a group of Chinese orphans. Meanwhile, Trixie returns to Poplar refreshed and is shocked to discover that many mothers no longer want to give birth at home.

Valerie帮助一位挣扎的母亲接受她儿子的出生缺陷。Turner夫妇监督诊所的麻疹疫苗接种试验，因为团队正在准备迎接惠特森银行假期。

Hilda修女为满足身患绝症的病人的最后愿望而挖空心思，而Turner夫妇必须准备与May告别。Fred和Reggie对彼此都有秘密。

Mother Mildred and the Nonnatus House team head to the Outer Hebrides in response to a nursing shortage.

Julienne修女自愿在Nonnatus House安置四名实习医生，让他们进行产科文凭的实践，希望这一做法能提醒理事会，该院对社区是多么重要，并帮助消除拆除的威胁。

在Turner家，Shelagh接到了香港收养机构的电话，电话里传来了一个令人震惊的消息：May的过去有人来到了英国，想看看这个小女孩。

修女Julienne决定是时候处理此事了，因为议会来信说将削减对Nonnatus之家的资助，不再支付住宿费用，于是她去找Violet，参加她作为当地议员的一次公开会议。

The circus comes to Poplar, putting a magical spell on its residents. A delighted Shelagh is reacquainted with an old friend, and Trixie receives an unusual gift.

现在是1966年7月，英国正处于世界杯的热潮中。新的助产士学生Nancy颇有影响。

Nonnatus之家在努力接受Nancy的启示。Julienne修女在母院休年假，Hilda修女很高兴有机会掩护她，并以她的领导能力给人留下深刻印象。

在照顾一位孕妇时，Frances修女和Trixie修女震惊地得知白杨镇的住房危机正在恶化，这让Nonnatus团队发誓要为变革而奋斗。

对Turner一家来说，这是一个悲痛的时刻，因为Timothy准备去爱丁堡的医学院学习，Cyril收到了来自家乡的消息，促使他和Lucille考虑自己的未来。

与此同时，一个非常特别的婴儿出生了，他在一个亲密的家庭中造成了裂痕，并导致许多人开始计算他们的祝福。

Christmas promises to be a memorable one at Nonnatus House as Lucille and Cyril prepare for their upcoming winter wedding. The Nonnatus team are faced with their busiest Christmas Day ever as the Maternity Home is filled with expectant mums-to-be, each with their own challenging case. Luckily Mother Mildred is on hand to support the team.

Demolition work in Poplar uncovers a long-buried secret that leads to a testing and emotional case for the team. Sister Julienne takes on a sensitive delivery.

Sister Hilda and Dr Turner support a young father with a lung condition whose wife is planning a home birth, and discover he is also coping with the repercussions of a past trauma. Cyril looks for a job that will put his qualifications to good use, a first-time mother struggles to bond with her daughter, and Fred comes up with a way to keep the wards cool during a summer heatwave.

Nonnatus House suffers its biggest threat yet. But this time it’s not the bricks and mortar that are in danger, it’s the people.

Nonnatus House faces its darkest day after a tragic incident in the heart of Poplar. As the community rallies together, the team must overcome personal anguish to help the injured.

The Turners support a family still suffering the devastating effects of thalidomide, Miss Higgins is involved in an unexpected delivery, and the community stages a talent show.

The maternity home is thrown into chaos by an outbreak of gastroenteritis, and Nurse Crane fights to save her career. Meanwhile, Cyril encourages Reggie to seek help.

A pregnant mother with a chronic heart condition falls unwell, Nancy grows suspicious of a young father’s erratic behaviour, and Matthew prepares for a visit from his father.

Trixie supports an underage mother through a difficult time, Monica Joan welcomes an unusual guest to Nonnatus House, and Sister Veronica spearheads a new council initiative.

Dr Turner experiences the biggest test of his career, while Trixie’s approaching nuptials cause stress levels to escalate. Sister Julienne hatches a plan to save Nonnatus House.

As Poplar prepares for Christmas, Sister Monica Joan fears this could be her last. Dr Turner and the midwives deal with a complicated multiple birth, and Cyril helps a war veteran.

Sister Julienne cares for an expectant mother who has cerebral palsy. Nonnatus House kicks off its new midwifery training scheme with the arrival of four new pupil midwives.

Nurse Crane helps a struggling first-time mother accept her baby’s birth defect, and Violet’s bid to be mayor is thrown into turmoil by unforeseen circumstances.