Christmas promises to be a memorable one at Nonnatus House as Lucille and Cyril prepare for their upcoming winter wedding. The Nonnatus team are faced with their busiest Christmas Day ever as the Maternity Home is filled with expectant mums-to-be, each with their own challenging case. Luckily Mother Mildred is on hand to support the team.

Demolition work in Poplar uncovers a long-buried secret that leads to a testing and emotional case for the team. Sister Julienne takes on a sensitive delivery.

At the monthly cytology clinic, Sister Frances comforts a young woman who is struggling with a life-changing diagnosis. Lucille supports a difficult mother.

Shelagh organises a special celebration to mark 100 years since the Order first arrived in Poplar - although Sister Hilda feels that she should have been in charge of the festivities. Nancy tackles the plight of meths drinkers living rough in Poplar, and Nurse Crane treats a young singer who is torn between two very different futures.

Sister Hilda and Dr Turner support a young father with a lung condition whose wife is planning a home birth, and discover he is also coping with the repercussions of a past trauma. Cyril looks for a job that will put his qualifications to good use, a first-time mother struggles to bond with her daughter, and Fred comes up with a way to keep the wards cool during a summer heatwave.

Trixie has been assigned to a complicated case involving a crane driver who was injured in a workplace accident and is now paraplegic. Meanwhile, Nancy and Sister Frances give a talk on the facts of life at a primary school, and Lucille's attendance at a straightforward delivery takes a distressing turn. Shelagh decides to organise a jumble sale to raise money to fix some broken playground equipment in the park. When Sister Julienne finds a suspicious item, chaos ensue

Sister Monica Joan seeks advice from a clairvoyant. Matthew is shocked to discover squatters in one of his warehouses, and Shelagh faces the most challenging delivery of her career.

Nonnatus House suffers its biggest threat yet. But this time it’s not the bricks and mortar that are in danger, it’s the people.

Nonnatus House faces its darkest day after a tragic incident in the heart of Poplar. As the community rallies together, the team must overcome personal anguish to help the injured.

The Turners support a family still suffering the devastating effects of thalidomide, Miss Higgins is involved in an unexpected delivery, and the community stages a talent show.

April 1968. Racial tensions cast a shadow over Poplar, Nancy’s eyes are opened when she supports a dying woman, and Nonnatus House welcomes a new sister.

Sister Julienne helps care for a first-time mother who is going through a challenging diagnosis. Lucille struggles with her own health, and Poplar celebrates the Whitsun Maypole.

Sister Veronica is shaken when a mother reveals a terrible truth about her marriage, whilst Shelagh cares for a baby with a life-threatening condition and Nancy harbours a secret.

The maternity home is thrown into chaos by an outbreak of gastroenteritis, and Nurse Crane fights to save her career. Meanwhile, Cyril encourages Reggie to seek help.

A pregnant mother with a chronic heart condition falls unwell, Nancy grows suspicious of a young father’s erratic behaviour, and Matthew prepares for a visit from his father.

Trixie supports an underage mother through a difficult time, Monica Joan welcomes an unusual guest to Nonnatus House, and Sister Veronica spearheads a new council initiative.

Poplar’s housing crisis deepens, bringing a sad case to the attention of the team, whilst a worrying disease outbreak directly impacts the residents of Nonnatus House.

Dr Turner experiences the biggest test of his career, while Trixie’s approaching nuptials cause stress levels to escalate. Sister Julienne hatches a plan to save Nonnatus House.

As Poplar prepares for Christmas, Sister Monica Joan fears this could be her last. Dr Turner and the midwives deal with a complicated multiple birth, and Cyril helps a war veteran.

Sister Julienne cares for an expectant mother who has cerebral palsy. Nonnatus House kicks off its new midwifery training scheme with the arrival of four new pupil midwives.

The team help a single mother whose flat is riddled with damp whilst Nancy and Dr Turner care for a Sylheti woman with an undiagnosed illness, and Matthew teaches Trixie how to drive.

Nurse Crane helps a struggling first-time mother accept her baby’s birth defect, and Violet’s bid to be mayor is thrown into turmoil by unforeseen circumstances.

Trixie makes a serious mistake at work, whilst the team work hard to help a Biafran family. Nancy delves into her family’s past as the world celebrates the moon landings.

A fun day at the seaside proves traumatic for the Turners and puts May’s future with them in jeopardy. Nurse Crane helps a young couple cope with a rare cancer diagnosis.

In his new role, Cyril faces his toughest challenge yet, whilst Matthew is summoned to a board meeting with his mother. Elsewhere, the pupil midwives prepare for their final exams.

Rosalind oversees the care of a teenage mum and uncovers a disturbing truth. Trixie and Matthew struggle with their change in fortune whilst Joyce receives an unexpected visitor.

Miss Higgins receives an unexpected visitor, and Sister Monica ruffles feathers. Poplar votes for its Mother of the Year.