The ITV News at 10.30 was the flagship news programme on British television network ITV, airing Monday to Friday at 10:30pm. It was produced by ITN. It was introduced into the ITV schedule as the ITV News at Ten-Thirty on 2 February 2004, following the demise of the ITV Nightly News.

There was a twenty-five minute broadcast of British national and international news, with a dedicated business, sports, and a review of the following morning' newspaper front-pages. It was followed by a five minute roundup of news from the ITV regions around the United Kingdom.