A scandalous family relationship leads to the deaths of nine people in the premiere of this true-crime series examining Southern murders.

21-year-old Geralyn DeSoto, a beautiful, young graduate student is brutally murdered in her Baton Rouge, LA home. Hers is but one of a string of slayings that have police racing against the clock to prevent a serial killer from striking again.

Beloved preacher Matthew Winkler and his loving wife, Mary, seem like two peas in a pod. But they’re hiding some scandalous secrets. Before long their horsing and carrying on will leave one of them dead and the other one running for the hills.

When Stephanie Bennett, a beautiful young woman, is killed in her apartment, Raleigh police must play a high-stakes game of cat-and-mouse to obtain a DNA sample from her suspected murderer.

After growing up in a tiny coal town and pulling herself up by her bootstraps, FBI secretary Melissa Galade Mooney had a whole lot to live for. When her promising life is suddenly cut short, friends wonder who would snuff out such a vivacious woman in her prime.

In the posh expanses of Virginia's Hunt Country, the fiery relationship between billionaire heiress Susan Cummings and her Argentine polo-playing boyfriend Roberto Villegas comes to a violent and shocking end.

When a retired couple, Derek and Nancy Haysom, is found murdered in their home in 1985, the town of Boonsboro, VA, fears they have a killer on the loose. Neighboring police agencies join forces to hunt down the monster and uncover clues that may have them heading right into the devil's den.

Genore Guillory is a generous soul and a friend to all, and when she doesn’t show up at work one day, her colleagues are immediately concerned. When police in Clinton, LA, discover her battered body but no enemies, they are left to wonder -- who loved Genore to death?

Robyn and Carol ('Sissy') are best friends who've always been by each other's side. When Robyn's husband, Brian Davis, is found murdered in Lake Charles, LA, Carol is right by her side. But police uncover Brian's racy past and a love for women that may have been his demise.