Naruto and Sasuke fight against Momoshiki Otsutsuki. Momoshiki gets defeated, but he's helped by Katasuke and his Scientific Ninja Tool. In the end, Boruto puts an end to Momoshiki's life. While dying, Momoshiki talks to Boruto and gives him the Karma Seal.

The White Snake Sage tells Boruto to bring back the "Reverse Scale" from Garaga, a troublesome snake. Boruto and his friends head deeper into Ryuchi Cave and are confronted by a giant serpent. It is Garaga, the very one they seek, but its sheer power has the gang backed into a corner. Meanwhile, Moegi reports that Mitsuki's disappearance might involve someone who has access to crucial village secrets.

Boruto and the others work together to obtain the Reverse Scale from Garaga. But the battle proves difficult, as Garaga has the power to sense the location of its enemies and turn them into stone. In the midst of battle, the team notices inconsistencies in Garaga's moves and comes up with a successful strategy to subdue him. Boruto is seized with a strange feeling and makes Garaga a proposition.

Instead of returning home with Boruto, Mitsuki stays with Kokuyou. During this time, Sekiei becomes sick and declines. To recover, Kokuyou returns to his comrades. During his absence, Sekiei asks Mitsuki to teach him what it means to be human. Meanwhile, the Fourth Tsuchikage Kurotsuchi, who had been visiting Ohnoki, her ailing grandfather, is attacked by mysterious assailants.

The team finds Ohnoki, but he flatly refuses to help. On top of which, they are attacked and separated. This leaves it up to each member to make it to the rendezvous point on their own. Meanwhile, Mitsuki is being shown around Kokuyou’s hideout.

In order to get out of the barrier, Boruto desperately searches for his heart of stone, but he has little success. Then he encounters Sekki, one of the Genbu Three that participated in the recent Chunin Exams. Sekki has also come to the training ground in order to find his heart of stone. Seeing their predicament, Ohnoki tries to help them.