시즌 정규 출연진 7

1. 

   Iain Armitage

   Sheldon Cooper

2. 

   Zoe Perry

   Mary Cooper

3. 

   Lance Barber

   George Cooper

4. 

   Montana Jordan

   Georgie Cooper

5. 

   Raegan Revord

   Missy Cooper

6. 

   Annie Potts

   Connie Tucker

7. 

   Jim Parsons

   Sheldon Cooper (voice)

특별출연 11

1. 

   Kate Flannery

   Nora

2. 

   Wayne Wilderson

   Dr. Gilbert

3. 

   Vernee Watson-Johnson

   Nurse Robinson

4. 

   Valerie Mahaffey

   Victoria MacElroy

5. 

   Danielle Pinnock

   Evelyn Ingram

6. 

   Mauricio Lara

   Ricky

7. 

   Chris Flanders

   Gary

8. 

   Kurt Koehler

   Nurse Pryor

9. 

   Kiva Jump

   Daisy

10. 

    Nick Alvarez

    Derek

11. 

    Doc Farrow

    Wayne Wilkins

제작진 6