Max creates chaos when he volunteers New Amsterdam to take over for a short-staffed neighboring hospital; Frome has a crisis of conscience about the funding for a hospital garden; an eager resident learns a secret about Bloom.

Max continues to work to solve underlying problems within the hospital despite his continuing struggles with treatment. Meanwhile, Reynolds makes the choice to do a costly surgery to determine an elusive diagnosis and Bloom must face her personal demons head-on.

Max goes head-to-head with hospital administration when he comes up with a new plan for patients without insurance. Iggy struggles with an accusation brought against him. Sharpe navigates her role as deputy medical director.

When Iggy and Kapoor discover a patient might be suffering from lead poisoning, they are forced to take on the city. Meanwhile, Max's unsolicited attempts to help a patient backfires.

Max and Luna make friends in an unexpected place as Max struggles with the realities of being a single father. Meanwhile, Kapoor takes a big step in order to help his family.

Reynolds receives a dramatic offer. Max scours the hospital after he misplaces his wedding ring. Iggy contemplates a serious life change. Bloom learns some potentially life-changing news about Leyla.

Max and Sharpe go public with their relationship at the hospital. The team struggles to handle an overcrowded and understaffed ICU. Iggy's overly critical feedback alienates his residents.

Max and Helen adjust to sharing their lives and problems, including the challenge of Helen's mother. Bloom and Reynolds treat a family after their horrific car accident lands them in the ED. Iggy and Trevor reach a new understanding in their business relationship.

The New Amsterdam team continues to deal with the consequences of their big night out. Max and Helen discuss options for their future. Martin finally learns Iggy's secret. Bloom helps Leyla avoid a life-changing situation. Reynolds and Dr. Malvo define their relationship going forward.

Max mandates a personal health day for the staff at New Amsterdam and meets with surprising resistance. Reynolds finds himself intrigued by a persuasive new member of the staff. Bloom struggles with job stress after being taken off an essential medication. Iggy goes on his first date. Max convinces Wilder to get much needed surgery.