Sharpe struggles when a case hits too close to home. Frome uncovers a patient's surprising past. Reynolds makes progress in his personal life after some difficult news.

Reynolds struggles to help a young cystic fibrosis patient with curious symptoms. Kapoor finally comes face-to-face with Ella after their awkward encounter. Sharpe takes a major step in her personal life.

Max goes head-to-head with hospital administration when he comes up with a new plan for patients without insurance. Iggy struggles with an accusation brought against him. Sharpe navigates her role as deputy medical director.

Max works to find a new normal three months after the accident and the birth of his daughter. Kapoor grapples with the stigma of aging. Iggy has a successful day that inspires a life-changing idea. Reynolds deals with an unreliable new intern.

Max takes a chance on a new assistant and goes toe-to-toe with the board on a new plan; Iggy struggles to figure out what is causing a unit-wide illness; Kapoor receives some shocking news.

When Iggy and Kapoor discover a patient might be suffering from lead poisoning, they are forced to take on the city. Meanwhile, Max's unsolicited attempts to help a patient backfires.

When Kapoor introduces a patient to Iggy's PTSD group, a creative treatment plan causes turmoil. Sharpe discovers a long-kept secret regarding a patient.

Sharpe lands in hot water when she goes out on a limb for a patient. Max's grief comes to a head. Bloom takes a major step in her recovery.

When an inmate comes in with an entirely preventable illness, Max, Sharpe, and Iggy head directly to the source - Rikers Island. Meanwhile, Bloom struggles with her recovery, and Reynolds gets news that could change his life.

Max and Luna make friends in an unexpected place as Max struggles with the realities of being a single father. Meanwhile, Kapoor takes a big step in order to help his family.

The doctors stop at nothing to help their patients, following a shocking realization that prompts a change in the hospital. Meanwhile, Reynolds must make an important decision in his career.

When tasked with turning the opioid epidemic around, Max shuts down the ED and proposes a massive change. Meanwhile, Sharpe goes great lengths to prove a point.

Max, Bloom and Reynolds frantically recount a patient's past encounter that could throw them into a massive lawsuit. Meanwhile, Iggy confronts a local middle school about its teaching policies, and Kapoor lets his superstitions take over.

Max searches for a solution to crowdfunding after his eye-opening appearance in a viral "Go Fund Me" video. Reynolds takes his last laps at the hospital while Kapoor helps a former pilot deal with his life as a paraplegic.

When multiple patients throughout the hospital begin to show similar, alarming symptoms, Sharpe and Bloom scramble to figure out the root of the issue. Iggy tries to create peace for a divorced couple in a dangerous situation and Kapoor experiences a flirtatious encounter. Meanwhile, Max meets a child with a rare muscular disease and desperately tries to get him into the only clinical trial in the country that could extend his life.

Max is forced to face the heartbreaking consequences of one of his policies. Bloom comes to a startling realization about Iggy.

Max is on a mission to fix systemic racism at New Amsterdam. Bloom treats a patient who reminds her that things aren't as they seem. Sharpe is overwhelmed while tending to a family matter. Reynolds tries to keep his composure while treating a father and son.

Max is forced to examine the inequities in child labor for women of color. Bloom must deal with an overcrowded ED. Sharpe helps Dr. Agnes Kao with a gut-wrenching diagnosis. Reynolds finds himself experiencing something new on the job.

Max reckons with New Amsterdam's past. Bloom and Reynolds treat a patient in an unconventional relationship. Sharpe decides to take a stricter approach to parenting her frustrated teenage niece. Iggy tries to connect with a patient desperate to have gastric bypass surgery.

Reynolds receives a dramatic offer. Max scours the hospital after he misplaces his wedding ring. Iggy contemplates a serious life change. Bloom learns some potentially life-changing news about Leyla.

Max and Sharpe go public with their relationship at the hospital. The team struggles to handle an overcrowded and understaffed ICU. Iggy's overly critical feedback alienates his residents.

Max advises a young student at a science fair but encounters legal complications with her brilliant invention. Bloom encourages Dr. Shinwari to be more aggressive in the ED. Iggy gets a lesson in humility. Brantley has a surprise for the staff.

Max struggles with a new fiscal reality at the hospital. Dr. Sharpe is on a mission to provide follow-up cancer screenings for patients before it’s too late. Bloom grapples with Dr. Shinwari’s new overnight schedule. Reynolds has an interesting conversation with Dr. Malvo about their future.

Max takes drastic measures to help several undocumented immigrants after a fire destroys the church where had sought refuge; Sharpe and Malvo assist a patient with a life threatening condition; Reynolds is conflicted about his new position.

As the team gathers to mourn the loss of someone dear, Max and Helen realize the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision while Reynolds decides to take his concerns for his patients to a new level. Dr. Fuentes once again reminds the New Amsterdam team who is in control.

Max formulates a bold plan to help New Amsterdam before it’s too late. Reynolds and Dr. Fuentes fight over the best way to handle a risky surgery. Dr. Wilder asks Dr. Castries for help with a patient with terminal cancer. Iggy helps a father and son deal with vastly different views on a shared trauma.

The New Amsterdam team continues to deal with the consequences of their big night out. Max and Helen discuss options for their future. Martin finally learns Iggy's secret. Bloom helps Leyla avoid a life-changing situation. Reynolds and Dr. Malvo define their relationship going forward.

Max orchestrates a plan to get Dr. Fuentes terminated from New Amsterdam once and for all. Helen confronts her medical complication. Iggy helps two patients deal with a breakup, which forces him to consider his own marriage. Bloom and Dr. Castries reach an understanding.

Max discovers the extent to which Dr. Fuentes' cuts are severely damaging New Amsterdam and decides it's now or never. Iggy takes an unconventional approach to reach a young patient in need. Reynolds and Wilder perform a risky, life-saving surgery on unborn twins.

Bloom, Iggy and Reynolds rally around Max as he deals with the fallout from Helen’s decision. Bloom gives extra space to Leyla, but she’s in for a surprise. Reynolds and Wilder help a young terminal patient realize his dream to star in a Bollywood show. Iggy has a breakthrough with a challenging patient.

Max tests a bold new cost-saving program that could help both New Amsterdam and its neediest patients. Wilder struggles with a patient’s decision to refuse life-saving surgery. Reynolds comes to an important realization about his father’s behaviors. Iggy takes the leap into online dating.

The New Amsterdam staff grapple with the aftermath of the recent Supreme Court decision on abortion rights. Wilder counsels a woman whose pregnancy puts her life in danger. At Brantley's urging, Max endeavors to find a healthcare solution for out-of-state patients. Bloom reveals monumental news to Reynolds.

Reynolds gets creative to help a prospective mother in need. Max takes a chance with Wilder and learns a hard truth. Bloom treats a young brother and sister in dire straits. Iggy reaches a decision about Martin.

Reynolds finds himself caught between a chance for love and an opportunity to spend precious time with his father. Realizing the consequences of her actions, Bloom makes an unexpected move forward with her sister. Max helps an ICU intern struggling with the loss of a patient. Dr. Wilder receives an offer that forces her to choose between her community and her career.