A visiting journalist picks at the hospital's flaws while shadowing Max; Bloom and Reynolds have a major disagreement after Bloom makes a call against protocol; Kapoor confronts issues from his past.

With a big domino transplant procedure on the line, Max must decide if he can be present in the hospital while also dealing with his illness. Meanwhile, a bond with a patient makes Bloom consider her personal life and Iggy makes progress on a long-standing case.

A patient's treatment plan takes an unexpected turn when Max gets overly invested. Meanwhile, Reynolds celebrates his birthday with some help from the hospital and Kapoor grapples with a case that hits close to home.

Reynolds confronts a difficult episode from his past. Max distracts himself from chemotherapy by taking on the case of a frequent-flyer patient. Frome helps a young man suffering from severe delusions. Sharpe worries about Bloom's attempt to detox.

Max continues to work to solve underlying problems within the hospital despite his continuing struggles with treatment. Meanwhile, Reynolds makes the choice to do a costly surgery to determine an elusive diagnosis and Bloom must face her personal demons head-on.

Max takes a chance on a new assistant and goes toe-to-toe with the board on a new plan; Iggy struggles to figure out what is causing a unit-wide illness; Kapoor receives some shocking news.

As the team gathers to mourn the loss of someone dear, Max and Helen realize the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision while Reynolds decides to take his concerns for his patients to a new level. Dr. Fuentes once again reminds the New Amsterdam team who is in control.