Elenco principal da temporada 6

1. 

   Ryan Eggold

   Max Goodwin

2. 

   Janet Montgomery

   Lauren Bloom

3. 

   Jocko Sims

   Floyd Reynolds

4. 

   Tyler Labine

   Iggy Frome

5. 

   Freema Agyeman

   Helen Sharpe

6. 

   Anupam Kher

   Vijay Kapoor

Convidados Especiais 23

1. Melanie Arii Mah

   Dr. Brill

2. Jenelle Chu

   Justine Siefert

3. 

   Cole Tristan Murphy

   Trey Masterson

4. 

   Harry Bouvy

   Dr. Eliraz

5. Natasha Sen

   Pediatric Nurse

6. 

   Austin Pendleton

   Eli Pembroke

7. 

   Kevin Interdonato

   Galatin

8. 

   Graceann Dorse

   Trey's Mother

9. 

   Ana Villafañe

   Valentina Castro

10. 

    Alison Luff

    Alice Healy

11. 

    Yvette Ganier

    Linda Weber

12. 

    Lily Du

    Lawan Panyacosit

13. Anastacia McCleskey

    Phylicia Elder

14. 

    Kim Ramirez

    Alicia Smith

15. 

    Sarafina King

    Nokic

16. 

    Alejandro Hernandez

    Casey Acosta

17. 

    Debra Monk

    Karen Brantley

18. 

    Dierdre Friel

    Ella

19. 

    Marissa Matrone

    Margaret Baker

20. 

    Anna Suzuki

    Sandra Fall

21. Joseph Cassese

    Trey's Dad

22. 

    Sue Jin Song

    Dr. Shanai

23. 

    Jeff Kim

    Alan Kapralien

Equipa técnica 3