Season 1 of U-Prince The Series premiered on January 1, 2016.

P'Sibtit is a "bad boy", a charming cowboy from the Faculty of Agriculture. He is Prikkang's first love, and she is his. But she has become a down-to-earth girl who dislikes narcissistic and arrogant people (like P'Sibtit who treats women like toys to be seduced and then left). When they meet again, they start off on the wrong foot. He takes her cold demeanor as a challenge and tries to win her over. But can old habits be changed? Does this playboy even have the emotional depth to truly love?

Season 2 of U-Prince The Series premiered on July 17, 2016.

Thesis is a second-year student at the Faculty of Veterinary Science. One rainy day he meets Suaysai, a girl who is afraid of rain. They become great friends and something even closer. But Suaysai's fear of the rain complicates everything. So Thesis decides to protect Suaysai from everything she fears even if he is hurt and they are torn apart.

Season 3 of U-Prince The Series premiered on August 14, 2016.

T-Rex is majoring in Geology at the Faculty of Science. He is known for being a huge fan of dinosaurs. One day he falls in love with a girl and decides to persistently pursue her, especially after he finds out that she has a boyfriend who treats her badly.

Season 4 of U-Prince The Series premiered on September 11, 2016.

P'Dash, a student at the Faculty of Culinary Arts, is a very talented cook who needs a new place to live. His friend T-Rex helps him to find a new apartment with one condition. That condition is a room mate: Renee, a free-spirited and lazy girl who studies at the Faculty of Arts and writes novels. At first, they don't get along, but that changes as they spend more and more time together. What will it take for them to recognize their feelings for each other?

Season 5 of U-Prince The Series premiered on October 9, 2016.

Teddy is a lonely, frugal man who meets flighty Chompink when she attempts to steal school money. He is disgusted. But as time passes, he begins to realize that money is not the most important thing, what matters is love. Despite all the love he feels, they will have to dodge many obstacles to be together.

Season 6 of U-Prince The Series premiered on December 18, 2016.

Khun Hawk is a grumpy aviation student from the Faculty of Engineering. He is cold and rarely expresses any emotion. When he is interviewed at Palmer Airlines, the owner requests that Khun Hawk befriend his spoiled daughter, the actress Aurora. She is full of herself and expects to be called "princess". But she also very lonely and tends to hide her true feelings behind a smile. With such contrasting personalities, can they help each other?

Season 7 of U-Prince The Series premiered on January 15, 2017.

Sung dreams of making Kiran, from the comm-arts department, her boyfriend. Until one day, Sung was hit by a tricycle and made a promise with the god of death. The god of death sent her back to the mortal world and gave her some kind of divine power. But for some reason, everytime she have physical contact with Kiran, Sung will go into trance.

Season 8 of U-Prince The Series premiered on February 12, 2017.

Kiryu Weller is an outgoing and friendly second-year student from the Faculty of Humanities. He becomes interested in Pinyin, his junior who transferred from China. However, she has a completely opposite personality - she is introverted, anxious, without friends and shy. At first, Pinyin finds Kiryu's intrusion overwhelming but slowly they start falling for each other.

Season 9 of U-Prince The Series premiered on March 12, 2017.

Firstclass is the first student to earn straight A's at the Faculty of Law in the last decade. He is very serious and strict when it comes to punctuality, which can be seen from the fact that one of his hobbies is collecting watches and clocks.

Minute is a self-centered, spoiled rich girl whose world crashes when her family files for bankruptcy. To survive (and avoid living in a squalid room), she pretends to be Firstclass's gay brother's girlfriend. She is paid a monthly stipend to live in their apartment. However, it seems that Minute and Firstclass cannot stand being in each other's presence without fighting. How can they get along?

Season 10 of U-Prince The Series premiered on April 9, 2017.

Mel B is dumped by her boyfriend Theo. The same day, she meets Hippy, a rock band's singer. He wants her Beatles t-shirt but as an exchange for it, he must pretend to be her boyfriend for five days.

Season 11 of U-Prince The Series premiered on May 7, 2017.

Cherrymilk, a young fashion lover, is forced to study Political Science by an order from her father. During a class, her teacher asked her to do a project but ended up being punished by her father.

To survive, she looks for Survey, a young man who is the only one that has the solution to all her problems. Over time, she falls in love but later learns that he is about to get married.

Season 12 of U-Prince The Series premiered on June 4, 2017.

Mantou, a Mafia boss's daughter, dreams of getting married after high school to the man she was betrothed to as a child. But that man has other dreams. So her parents try to arrange another marriage. This time the chosen groom is the son of another mafia boss.

At first, Mantou refuses since she feels nothing for Brian, not knowing that he has had a crush on her since they were children. However, Brian strives to win her love in the midst of jealousy, misunderstandings and a potentially devastating battle between Thailand's three major Mafia families.