After five long months, the passengers of Avenue 5 eagerly await their impending return to Earth­­ while behind the scenes, Ryan and the crew struggle to find a way to reveal the much longer timeline of their journey home. Later, a disgraced Karen comes to blows with a newly famous Frank.

With the ship facing a fiery threat, Billie hatches a plan that could just save some of the passengers… and the eels. Meanwhile, Iris makes a risky bid on Earth, Ryan finds himself in the middle of a three-way couples’ quarrel, and Mia shares some shocking news with Doug.

When the ship crosses paths with a rogue space station, Ryan and the crew jump at the opportunity to socialize, while Billie angles for help with Avenue 5’s mounting eel problem. Then, after Rav discovers the true purpose of Storm Falcon’s mission, Ryan must steer his team through a difficult moral quandary.

Now stuck with an unsavory stowaway, Ryan and Billie lock down the ship – with potentially dangerous consequences. Meanwhile, Iris and Judd attempt to blackmail Lucas, Karen claws her way back to the top, and Frank fends off an attack.

After a failed revolt, the passengers put the ship’s leadership to a vote, bringing forth a pack of unlikely candidates. Meanwhile, back on Earth, the Office of the Other President proposes a plan that could spell doom for Avenue 5.

With a "new" leader at the helm, life on deck reaches a semi-status quo – until the discovery of a mysterious blip and dissident uprising threaten to upend the passenger’s tenuous peace. Later, life imitates art as the shocking conclusion of TV’s Avenue 5 puts those aboard the real ship in peril.