Nite Lite Live is a Christian nightly television open-line call-in show in Canada hosted by Paul Willoughby. It is a programme on the Crossroads Television System. The show is 2½ hours long, commercial-free, from 2 A.M. to 4:30 A.M. EST. Nite Lite Live used to air seven days a week, 365 days a year. But, due to the 2009 economic recession the show was cut back to five days a week with re-runs being shown on the weekends. There are also frequent guest hosts.

People can call in and can talk to the host about any questions and/or concerns they may have in their lives; they can also ask questions regarding Christianity or the Bible; and they can also ask for prayer. There also tends to be a certain theme or question of the night which callers can comment on.

Hosts include, Pastor Paul Willoughby, Pastor Dominic Vitale, Pastor Jamal and Pam, and many others. The call screener is Neal, who will notify you upon calling that there is a '10 second delay', so in the even you swear, your cursing will be censored this is in response to a number of atheists prank calling the station and uploading to YouTube.