《生活对我下手了》是爱奇艺出品，春风画面制作的全国首部竖屏微网剧。该剧是由开心麻花艺人乌日娜与新晋导演李亚飞联合执导，辣目洋子、刘背实领衔主演，包贝尔、马丽、沈凌、许君聪、野食小哥、毒角show、除了我都是猪等共同出演的青春爆笑喜剧。

Yang Zi comes from a broken family. Her family life revolves around quarrelling with her older brother Liu Bei Shi. In love, she is a perpetual loser. She either meets men who do not know a thing about women or men who cling onto women. At work, Yang Zi has the heart but lacks the skill to succeed. In her social life, Yang Zi has the best type of friends. They are the kind of people who borrow money but never return them. Every unusual encounter for Yang Zi has become a part of her daily norm.

A story about a woman who finds herself in outrageous situations when life continually messes with her.