A genetically mutated ape escapes from a top secret facility and wreaks havoc in Hollywood.

Dr. Bernard Adrian is a kindly scientist who seeks to cure a young woman's polio. He needs human spinal fluid to complete the formula for his experimental serum. Meanwhile, a vicious circus ape has broken out of its cage, and is terrorizing the townspeople. Can there be a connection?

Six American grad students have arrived in Africa to study apes with a renowned professor. But after setting up camp in a jungle clearing, they soon become witness to the carnage inflicted by the strange and remote species.

Out of the Mystic Temples of Old India crept this terrible Monster to wreak vengeance of the Hindu Gods. One by one its victims fell with not a trace of the bloody assassin.