Out of the Mystic Temples of Old India crept this terrible Monster to wreak vengeance of the Hindu Gods. One by one its victims fell with not a trace of the bloody assassin.

Dr. Bernard Adrian is a kindly scientist who seeks to cure a young woman's polio. He needs human spinal fluid to complete the formula for his experimental serum. Meanwhile, a vicious circus ape has broken out of its cage, and is terrorizing the townspeople. Can there be a connection?

Six American grad students have arrived in Africa to study apes with a renowned professor. But after setting up camp in a jungle clearing, they soon become witness to the carnage inflicted by the strange and remote species.

A genetically mutated ape escapes from a top secret facility and wreaks havoc in Hollywood.